The Nanoscale Spectroscopy and Photoinduced Phenomena Lab
Research Highlights:
Host-guest interaction and applications in biological environments
The bound guest molecules to corresponding hosts may change the morphology of the latter subsequently generating molecular suprastructures that create provisions for trapping ions. The dynamics of the process is understood using various spectroscopic techniques.
Synthesis and application of metal nanoparticles and nanoclusters in drug delivery
We synthesize noble metal nanoparticles and nanoclusters and apply them in drug delivery following biological compatibility. The metal nanoclusters show fluorescence signals as opposed to the nanoparticles that makes them usable as bio-markers. Guest-host chemistry can be applied to develop bio-remedies for various physiological malfunctions.
Carbon nanoparticles in photoinduced energy/electron transfer
Photoinduced electron transfer is a smart concept to learn as this encompasses various applications including energy harvesting devices. We use carbon based nanomaterials, including nanoparticles, nanotubes and nanoplatelets to look into interactions with various energy donating/accepting substances in view of understanding the underlying dynamics.
Development of crystalline polymorphs for photophysical tuning
New organic compounds are synthesized in this venture through structural engineering and crystals are produced intuitively so that the materials can be used various applications including light guides, OLEDs, room temperature phosphorescent substances, etc.
Fluorescence Lifetime Imaging (FLIM) and Fluorescence Correlation Spectroscopy (FCS)
These microscopy based techniques are used in our laboratory to justify the positioning of various guests in bio-compatible hosts, such as, lipid vesicles. Entrapment of the fluorescent species within bilayers alters the inherent photophysics of the guests that are significant to understand before applications to drug delivery.
Selected Recent Publications:
A. Chatterjee, A. Joy and P. Purkayastha, microviscosity-assisted disaggregation of a model ophthalmic drug and FRET-controlled singlet oxygen generation in lyotropic liquid crystals, Langmuir 2024, 40, 4321-4332.
P. Pattanayak, A. Nandi, R. Patra and P. Purkayastha, Triplet Exciton Harvesting in Water by a Structurally Simple Organic Phosphor with Sustained Afterglow and Lifetime Tunability, Adv. Opt. Mater. 2024, 12, 2302155.
P. Pattanayak, A. Nandi and P. Purkayastha, Polymorphism-mediated regulation of thermally activated delayed fluorescence and room temperature phosphorescence via intra and intermolecular charge transfer, Chem. Mater. 2023, 35, 22, 9799–9805.
M. Mukherjee, A. Chatterjee, S. Bhunia and P. Purkayastha, Hydrophobic Chain-Induced Conversion of Three-Dimensional Perovskite Nanocrystals to Gold Nanocluster-Grafted Two-Dimensional Platelets for Photoinduced Electron Transfer Substrate Formulation, J. Phys. Chem. Lett. 2023, 14, 8251-8260.
P. Pattanayak, A. Nandi, S. K. Seth and P. Purkayastha, Heavy-Element-Free Triplet Accessibility in Pyrene-Core Compounds at Room Temperature by Microcrystal Engineering, J. Mater. Chem. C 2023, 11, 11252-11261.
I. Mukherjee, H. Dekate and P. Purkayastha, On the Effect of Folic Acid Derived Carbon Nanodots in Modulating the Noncanonical I-Motif DNA Structures, ACS Appl. Nano Mater. 2023, 6, 6380-6387.
A. Chatterjee, A. K. Sharma, S. Pramanick, O. S. Jaykishan and P. Purkayastha, Dual stimuli responsive BSA-coated silver nanocluster-driven “FRET on-off” within niosomal membrane: detailed design and mechanism, J. Phys. Chem. C, 127, 2023, 797-806.